Higher COVID-19 death rates in the southern U.S. due to behavior variations, study finds

Journal Reference: Michael A. Stoto, Samantha Schlageter, John D. Kraemer. COVID-19 mortality in the United States: It’s been two Americas from the start. PLOS ONE, 2022; 17 (4): e0265053 DOI: 10.1371/journal.pone.0265053 The study, by Georgetown University’s School of Nursing & Health Studies researchers, appeared April 28, 2022, in PLOS ONE. Excess mortality, which helps account … Read more

Scientists call for cap on production to end plastic pollution

Journal Reference: Melanie Bergmann, Bethanie Carney Almroth, Susanne M. Brander, Tridibesh Dey, Dannielle S. Green, Sedat Gundogdu, Anja Krieger, Martin Wagner, Tony R. Walker. A global plastic treaty must cap production. Science, 2022; 376 (6592): 469 DOI: 10.1126/science.abq0082 Now, after the United Nations’ historic decision to adopt a global treaty to end plastic pollution earlier … Read more

Gene mutations that contribute to head and neck cancer also provide ‘precision’ treatment targets

Journal Reference: Hoi-Lam Ngan, Chun-Ho Law, Yannie Chung Yan Choi, Jenny Yu-Sum Chan, Vivian Wai Yan Lui. Precision drugging of the MAPK pathway in head and neck cancer. npj Genomic Medicine, 2022; 7 (1) DOI: 10.1038/s41525-022-00293-1 Keys to targeting that vulnerability include individualized genomic analysis to identify a patient’s specific mutation, and finding the drugs … Read more

Unravelling the origins of the human spine

Journal Reference: Marina Sanaki-Matsumiya, Mitsuhiro Matsuda, Nicola Gritti, Fumio Nakaki, James Sharpe, Vikas Trivedi, Miki Ebisuya. Periodic formation of epithelial somites from human pluripotent stem cells. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-29967-1 The spinal column consists of 33 vertebrae, which form pairs of precursor structures called somites. Somites give rise to not only our … Read more

Sampling the deep graveyard of Earth’s earliest crust

Journal Reference: Jonas Tusch, J. Elis Hoffmann, Eric Hasenstab, Mario Fischer-Gödde, Chris S. Marien, Allan H. Wilson, Carsten Münker. Long-term preservation of Hadean protocrust in Earth’s mantle. Proceedings of the National Academy of Sciences, 2022; 119 (18) DOI: 10.1073/pnas.2120241119 This finding is unexpected because the plate tectonic regime of our planet progressively recycles crustal material … Read more

Accurately monitoring subsurface carbon dioxide storage

Journal Reference: Keyla Gonzalez, Siddharth Misra. Unsupervised learning monitors the carbon-dioxide plume in the subsurface carbon storage reservoir. Expert Systems with Applications, 2022; 201: 117216 DOI: 10.1016/j.eswa.2022.117216 Texas A&M University researchers proved that unsupervised machine-learning methods could analyze the sensor-gathered data from a geological carbon-storage site and rapidly depict the underground CO2 plume locations and … Read more

New research identifies blood biomarker for predicting dementia before symptoms develop

Journal Reference: Emer R. McGrath, Alexa S. Beiser, Adrienne O’Donnell, Qiong Yang, Saptaparni Ghosh, Mitzi M. Gonzales, Jayandra J. Himali, Claudia L. Satizabal, Keith A. Johnson, Russell P. Tracy, Sudha Seshadri. Blood Phosphorylated Tau 181 as a Biomarker for Amyloid Burden on Brain PET in Cognitively Healthy Adults. Journal of Alzheimer’s Disease, 2022; 1 DOI: … Read more

Neuronal plasticity in chronic pain-induced anxiety revealed

Journal Reference: Naoki Yamauchi, Keiichiro Sato, Kenta Sato, Shunsaku Murakawa, Yumi Hamasaki, Hiroshi Nomura, Taiju Amano, Masabumi Minami. Chronic pain–induced neuronal plasticity in the bed nucleus of the stria terminalis causes maladaptive anxiety. Science Advances, 2022; 8 (17) DOI: 10.1126/sciadv.abj5586 Chronic pain is persistent and inescapable, and can lead to maladaptive emotional states. It is … Read more

Lipidomics provides new biomarkers for cardiovascular disease and Type 2 diabetes

Journal Reference: Fabian Eichelmann, Laury Sellem, Clemens Wittenbecher, Susanne Jäger, Olga Kuxhaus, Marcela Prada, Rafael Cuadrat, Kim G. Jackson, Julie A. Lovegrove, Matthias B. Schulze. Deep Lipidomics in Human Plasma – Cardiometabolic Disease Risk and Effect of Dietary Fat Modulation. Circulation, 2022; DOI: 10.1161/CIRCULATIONAHA.121.056805 Cardiovascular disease is the leading cause of death worldwide, accounting for … Read more

Anesthetic drastically diverts the travels of brain waves

Journal Reference: Sayak Bhattacharya, Jacob A. Donoghue, Meredith Mahnke, Scott L. Brincat, Emery N. Brown, Earl K. Miller. Propofol Anesthesia Alters Cortical Traveling Waves. Journal of Cognitive Neuroscience, 2022; 1 DOI: 10.1162/jocn_a_01856 Imagine the conscious brain as a sea roiling with the collisions and dispersals of waves of different sizes and shapes, swirling around and … Read more

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