Anesthetic drastically diverts the travels of brain waves

Journal Reference: Sayak Bhattacharya, Jacob A. Donoghue, Meredith Mahnke, Scott L. Brincat, Emery N. Brown, Earl K. Miller. Propofol Anesthesia Alters Cortical Traveling Waves. Journal of Cognitive Neuroscience, 2022; 1 DOI: 10.1162/jocn_a_01856 Imagine the conscious brain as a sea roiling with the collisions and dispersals of waves of different sizes and shapes, swirling around and … Read more

Study reveals set of brain regions that control complex sequences of movement

Journal Reference: Duo Xu, Mingyuan Dong, Yuxi Chen, Angel M. Delgado, Natasha C. Hughes, Linghua Zhang, Daniel H. O’Connor. Cortical processing of flexible and context-dependent sensorimotor sequences. Nature, 2022; 603 (7901): 464 DOI: 10.1038/s41586-022-04478-7 The research, they say, could one day help scientists find ways to target those regions in people and restore motor function … Read more

Unexpected protein could play role in common brain disorder

Journal Reference: Yi Xiao Jiang, Qin Cao, Michael R. Sawaya, Romany Abskharon, Peng Ge, Michael DeTure, Dennis W. Dickson, Janine Y. Fu, Rachel R. Ogorzalek Loo, Joseph A. Loo, David S. Eisenberg. Amyloid fibrils in disease FTLD-TDP are composed of TMEM106B not TDP-43. Nature, 2022; DOI: 10.1038/s41586-022-04670-9 Now, UCLA biochemists have discovered such fibrils in … Read more

Calming overexcited neurons may protect brain after stroke

Journal Reference: Laura Ibanez, Laura Heitsch, Caty Carrera, Fabiana H. G. Farias, Jorge L. Del Aguila, Rajat Dhar, John Budde, Kristy Bergmann, Joseph Bradley, Oscar Harari, Chia-Ling Phuah, Robin Lemmens, Alessandro A. Viana Oliveira Souza, Francisco Moniche, Antonio Cabezas-Juan, Juan Francisco Arenillas, Jerzy Krupinksi, Natalia Cullell, Nuria Torres-Aguila, Elena Muiño, Jara Cárcel-Márquez, Joan Marti-Fabregas, Raquel … Read more

Genomic sequencing is changing prognosis, treatment for patients with brain cancer

Journal Reference: Yalan Zhang, Calixto-Hope G Lucas, Jacob S Young, Ramin A Morshed, Lucie McCoy, Nancy Ann Oberheim Bush, Jennie W Taylor, Mariza Daras, Nicholas A Butowski, Javier E Villanueva-Meyer, Soonmee Cha, Margaret Wrensch, John K Wiencke, Julieann C Lee, Melike Pekmezci, Joanna J Phillips, Arie Perry, Andrew W Bollen, Manish K Aghi, Philip Theodosopoulos, … Read more

An ocean in your brain: Interacting brain waves key to how we process information

Journal Reference: Sergei Gepshtein, Ambarish S. Pawar, Sunwoo Kwon, Sergey Savel’ev, Thomas D. Albright. Spatially distributed computation in cortical circuits. Science Advances, 2022; 8 (16) DOI: 10.1126/sciadv.abl5865 “We now have a new understanding of how the computational machinery of the brain is working,” says Albright, the Conrad T. Prebys Chair in Vision Research and director … Read more

Enzyme prevents brain activity from getting out of control

Journal Reference: Johannes Alexander Müller, Julia Betzin, Jorge Santos-Tejedor, Annika Mayer, Ana-Maria Oprişoreanu, Kasper Engholm-Keller, Isabelle Paulußen, Polina Gulakova, Terrence Daniel McGovern, Lena Johanna Gschossman, Eva Schönhense, Jesse R. Wark, Alf Lamprecht, Albert J. Becker, Ashley J. Waardenberg, Mark E. Graham, Dirk Dietrich, Susanne Schoch. A presynaptic phosphosignaling hub for lasting homeostatic plasticity. Cell Reports, … Read more

Study shows easy, computationally-light model can simulate complex brain cell responses

Journal Reference: Yota Tsukamoto, Honami Tsushima, Tohru Ikeguchi. Non-periodic responses of the Izhikevich neuron model to periodic inputs. Nonlinear Theory and Its Applications, IEICE, 2022; 13 (2): 367 DOI: 10.1587/nolta.13.367 Learning how neurons respond to different signals can further the understanding of cognition and development and improve the management of disorders of the brain. But … Read more

Study explores effects of extended spaceflight on brain

Journal Reference: Giuseppe Barisano, Farshid Sepehrband, Heather R. Collins, Steven Jillings, Ben Jeurissen, James A. Taylor, Catho Schoenmaekers, Chloë De Laet, Ilya Rukavishnikov, Inna Nosikova, Liudmila Litvinova, Alena Rumshiskaya, Jitka Annen, Jan Sijbers, Steven Laureys, Angelique Van Ombergen, Victor Petrovichev, Valentin Sinitsyn, Ekaterina Pechenkova, Alexey Grishin, Peter zu Eulenburg, Meng Law, Stefan Sunaert, Paul M. … Read more

A key brain region for substance use disorders now has a searchable atlas of distinct cell populations

Journal Reference: Robert A. Phillips, Jennifer J. Tuscher, Samantha L. Black, Emma Andraka, N. Dalton Fitzgerald, Lara Ianov, Jeremy J. Day. An atlas of transcriptionally defined cell populations in the rat ventral tegmental area. Cell Reports, 2022; 39 (1): 110616 DOI: 10.1016/j.celrep.2022.110616 The VTA is important for its role in the dopamine neurotransmission involved in … Read more

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