New tool reveals how immune cells find their targets

Journal Reference: Connor S. Dobson, Anna N. Reich, Stephanie Gaglione, Blake E. Smith, Ellen J. Kim, Jiayi Dong, Larance Ronsard, Vintus Okonkwo, Daniel Lingwood, Michael Dougan, Stephanie K. Dougan, Michael E. Birnbaum. Antigen identification and high-throughput interaction mapping by reprogramming viral entry. Nature Methods, 2022; DOI: 10.1038/s41592-022-01436-z MIT biological engineers have now devised an experimental … Read more

Researchers’ novel tool to help develop safer pesticides

Journal Reference: Jessica M. Lewer, Zachary R. Stickelman, Jessica H. Huang, John F. Peloquin, Jakub Kostal. Structure-to-process design framework for developing safer pesticides. Science Advances, 2022; 8 (13) DOI: 10.1126/sciadv.abn2058 The majority of commercial chemicals that enter the market in the United States every year have insufficient health and safety data. For pesticides, the U.S. … Read more

A simple diagnostic tool for gastrointestinal disorders

Journal Reference: Kewang Nan, Sahab Babaee, Walter W. Chan, Johannes L. P. Kuosmanen, Vivian R. Feig, Yiyue Luo, Shriya S. Srinivasan, Christina M. Patterson, Ahmad Mujtaba Jebran, Giovanni Traverso. Low-cost gastrointestinal manometry via silicone–liquid-metal pressure transducers resembling a quipu. Nature Biomedical Engineering, 2022; DOI: 10.1038/s41551-022-00859-5 Dysmotility disorders are usually diagnosed with a catheter containing pressure … Read more

Artificial intelligence tool may help predict heart attacks

Journal Reference: Andrew Lin, Nipun Manral, Priscilla McElhinney, Aditya Killekar, Hidenari Matsumoto, Jacek Kwiecinski, Konrad Pieszko, Aryabod Razipour, Kajetan Grodecki, Caroline Park, Yuka Otaki, Mhairi Doris, Alan C Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Evangelos Tzolos, Aakash Shanbhag, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K Tamarappoo, Sebastien Cadet, Stephan Achenbach, Stephen J … Read more

Optimizer tool designs, evaluates, maximizes solar-powered cooling systems

Journal Reference: N. Saravanan, M. Edwin. Optimization and experimental analysis of a solar powered adsorption refrigeration system using selective adsorbent/adsorbate pairs. Journal of Renewable and Sustainable Energy, 2022; 14 (2): 023702 DOI: 10.1063/5.0076645 In the Journal of Renewable and Sustainable Energy, by AIP Publishing, researchers from Anna University in India developed an optimizer tool to … Read more

Blood test as possible diagnostic tool for Alzheimer’s disease

Journal Reference: Zachary Winder, Tiffany L. Sudduth, Sonya Anderson, Ela Patel, Janna Neltner, Barbara J. Martin, Katherine E. Snyder, Erin L. Abner, Gregory A. Jicha, Peter T. Nelson, Donna M. Wilcock. Examining the association between blood‐based biomarkers and human post mortem neuropathology in the University of Kentucky Alzheimer’s Disease Research Center autopsy cohort. Alzheimer’s & … Read more

Inclusive new tool makes genomic research better reflect world’s diversity

Journal Reference: Jouni Sirén, Jean Monlong, Xian Chang, Adam M. Novak, Jordan M. Eizenga, Charles Markello, Jonas A. Sibbesen, Glenn Hickey, Pi-Chuan Chang, Andrew Carroll, Namrata Gupta, Stacey Gabriel, Thomas W. Blackwell, Aakrosh Ratan, Kent D. Taylor, Stephen S. Rich, Jerome I. Rotter, David Haussler, Erik Garrison, Benedict Paten. Pangenomics enables genotyping of known structural … Read more

New dental tool prototype can spot the acidic conditions that lead to cavities

Journal Reference: Manuja Sharma, Lauren K. Lee, Matthew D. Carson, David S. Park, Se W. An, Micah G. Bovenkamp, Jess J. Cayetano, Ian A Berude, Zheng Xu, Alireza Sadr, Shwetak N. Patel, Eric J. Seibel. O-pH: Optical pH Monitor to Measure Oral Biofilm Acidity and Assist in Enamel Health Monitoring. IEEE Transactions on Biomedical Engineering, … Read more

New data analysis tool uncovers important COVID-19 clues

Journal Reference: Manik Kuchroo, Jessie Huang, Patrick Wong, Jean-Christophe Grenier, Dennis Shung, Alexander Tong, Carolina Lucas, Jon Klein, Daniel B. Burkhardt, Scott Gigante, Abhinav Godavarthi, Bastian Rieck, Benjamin Israelow, Michael Simonov, Tianyang Mao, Ji Eun Oh, Julio Silva, Takehiro Takahashi, Camila D. Odio, Arnau Casanovas-Massana, John Fournier, Abeer Obaid, Adam Moore, Alice Lu-Culligan, Allison Nelson, … Read more

CROPSR: A new tool to accelerate genetic discoveries

Journal Reference: Hans Müller Paul, Dave D. Istanto, Jacob Heldenbrand, Matthew E. Hudson. CROPSR: an automated platform for complex genome-wide CRISPR gRNA design and validation. BMC Bioinformatics, 2022; 23 (1) DOI: 10.1186/s12859-022-04593-2 The genomes of crops are tailored by generations of breeding to optimize specific traits, and until recently breeders were limited to selection on … Read more

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